Tratamiento farmacológico en la fibromialgia

En este reciente estudio, publicado en Reumatismo 2007;59(4):280-291, pone de manifiesto que los últimos tratamientos que demuestran "eficacia" en la enfermedad de fibromialgia son;

-Anticonvulsionantes como pregabalina y gabapentina;

-Recapatadores duales de serotonina y norepinefrina; Duloxetina y milnacipran muestran ciertos resultados en el manejo de la enfermedad.

- Los resultados en las investigaciones clínica con antiinflamatorios han sido nulos para manejar el dolor en fibromialgia, y el resultado del tramadol asociado o no al acetomifen han dado buenos resultados.

 

Pharmacological treatment of fibromyalgia.

Cazzola M, Sarzi-Puttini P, Buskila D, Atzeni F. U.O. Reumatologia, Azienda Ospedaliera "L. Sacco", 20157 Milano, Italia. atzenifabiola@hotmail.com.

Fibromyalgia syndrome (FM) is a condition of chronic and diffuse muscular pain affecting particularly middle aged women. The aetiology of FM is not completely understood and it is currently considered a disorder of pain regulation. The most efficacious compounds include the tricyclic drugs and mixed reuptake inhibitors. Recent works suggest that the anticonvulsant medications pregabalin and gabapentin are also effective. Moreover, two serotonin and norepinephrine-reuptake inhibitors-duloxetine and milnacipran show encouraging results in treating FM symptoms. The results of clinical trials of anti-inflammatory medications have been generally disappointing, but three RCTs have found that tramadol (with or without acetaminophen) is effective in FM.

PMID: 18157284 

Acceso a el pdf en Italiano La terapia farmacologica della fibromialgia